For research use only. Not for therapeutic Use.
SSR411298 (Cat No.: I045497) is a potent, selective inhibitor of fatty acid amide hydrolase (FAAH), the enzyme responsible for degrading endocannabinoids such as anandamide. By blocking FAAH activity, SSR411298 increases endocannabinoid levels, enhancing cannabinoid receptor–mediated signaling involved in pain modulation, mood regulation, and neuroprotection. It has been investigated for potential therapeutic applications in anxiety, depression, neuropathic pain, and inflammatory disorders. SSR411298 is used in neuropharmacology and cannabinoid research to study the role of endocannabinoid metabolism in health and disease, offering a non-psychoactive approach to modulating the endocannabinoid system.
| CAS Number | 666860-59-9 |
| Synonyms | (2-amino-2-oxoethyl) N-[3-[5-(6-methoxynaphthalen-1-yl)-1,3-dioxan-2-yl]propyl]carbamate |
| Molecular Formula | C21H26N2O6 |
| Purity | ≥95% |
| InChI | InChI=1S/C21H26N2O6/c1-26-16-7-8-18-14(10-16)4-2-5-17(18)15-11-27-20(28-12-15)6-3-9-23-21(25)29-13-19(22)24/h2,4-5,7-8,10,15,20H,3,6,9,11-13H2,1H3,(H2,22,24)(H,23,25) |
| InChIKey | OGKKHZMANPWMSD-UHFFFAOYSA-N |
| SMILES | COC1=CC2=C(C=C1)C(=CC=C2)C3COC(OC3)CCCNC(=O)OCC(=O)N |
| Reference | [1]. Guy Griebel, et al. The selective reversible FAAH inhibitor, SSR411298, restores the development of maladaptive behaviors to acute and chronic stress in rodents. Sci Rep. 2018 Feb 5;8(1):2416. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
