SR2640 hydrochloride

• CAT Number: I010463
• CAS Number: 146662-42-2
• Molecular Formula: C23H19ClN2O3
• Molecular Weight: 406.86
• Purity: ≥95%
• Synonyms: 2-[3-(quinolin-2-ylmethoxy)anilino]benzoic acid;hydrochloride
• InChI: InChI=1S/C23H18N2O3.ClH/c26-23(27)20-9-2-4-11-22(20)24-17-7-5-8-19(14-17)28-15-18-13-12-16-6-1-3-10-21(16)25-18;/h1-14,24H,15H2,(H,26,27);1H
• InChIKey: KDSYWFCTUKABKE-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C=CC(=N2)COC3=CC=CC(=C3)NC4=CC=CC=C4C(=O)O.Cl

SR2640 hydrochloride（Cat No.:I010463）is a selective small molecule inhibitor that targets the transcription factor REV-ERBα, which plays a critical role in regulating circadian rhythms, metabolism, and inflammation. By modulating REV-ERBα activity, SR2640 hydrochloride can influence gene expression related to metabolic processes, including lipid and glucose homeostasis. This compound has shown potential for treating metabolic disorders such as obesity, type 2 diabetes, and non-alcoholic fatty liver disease. SR2640 hydrochloride also offers a promising approach for exploring the therapeutic modulation of circadian rhythm-related pathways in various diseases.