SR 144528

• CAT Number: R015582
• CAS Number: 192703-06-3
• Molecular Formula: C29H34ClN3O
• Molecular Weight: 475.20
• Purity: ≥95%
• Synonyms: (1S-endo)-5-(4-Chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-(1,3,3-trimethylbicyclo[2.2.1]hept-2-yl)-1H-Pyrazole-3-carboxamide
• Target: Neuronal Signaling
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethyl-2-bicyclo[2.2.1]heptanyl]pyrazole-3-carboxamide
• InChI: InChI=1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)/t22-,27-,29+/m1/s1
• InChIKey: SUGVYNSRNKFXQM-XRHWURSXSA-N
• SMILES: CC1=CC=C(C=C1)CN2C(=CC(=N2)C(=O)N[C@H]3[C@]4(CC[C@H](C4)C3(C)C)C)C5=CC(=C(C=C5)Cl)C

SR 144528（Cat No.:R015582）is a selective CB2 receptor antagonist that belongs to the class of synthetic compounds used to study the endocannabinoid system. It primarily targets the CB2 receptor, which is mainly expressed in immune cells and peripheral tissues. SR 144528 is widely used in pharmacological research to explore the role of CB2 receptors in immune response modulation, pain management, and inflammation. By blocking CB2 receptors, it helps to elucidate the therapeutic potential of cannabinoids in conditions such as neuropathic pain and autoimmune disorders.