SR-1114

• CAT Number: I044126
• CAS Number: 2769141-82-2
• Molecular Formula: C39H42N8O11S
• Molecular Weight: 830.86
• Purity: ≥95%
• Synonyms: N-cyclobutyl-2-[3-[2-[2-[2-[[2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetyl]amino]ethoxy]ethoxy]ethylsulfamoylamino]phenyl]imidazo[1,2-a]pyridine-6-carboxamide
• InChI: InChI=1S/C39H42N8O11S/c48-33-13-11-30(37(51)44-33)47-38(52)28-8-3-9-31(35(28)39(47)53)58-23-34(49)40-14-16-56-18-19-57-17-15-41-59(54,55)45-27-7-1-4-24(20-27)29-22-46-21-25(10-12-32(46)43-29)36(50)42-26-5-2-6-26/h1,3-4,7-10,12,20-22,26,30,41,45H,2,5-6,11,13-19,23H2,(H,40,49)(H,42,50)(H,44,48,51)
• InChIKey: WPVVPCVQEBQVLL-UHFFFAOYSA-N
• SMILES: C1CC(C1)NC(=O)C2=CN3C=C(N=C3C=C2)C4=CC(=CC=C4)NS(=O)(=O)NCCOCCOCCNC(=O)COC5=CC=CC6=C5C(=O)N(C6=O)C7CCC(=O)NC7=O

SR-1114（Cat No.:I044126）is a selective synthetic agonist of REV-ERBα, a nuclear receptor that plays a key role in regulating circadian rhythm, metabolism, and inflammatory responses. By binding to REV-ERBα, SR-1114 modulates the expression of target genes involved in lipid metabolism, glucose homeostasis, and immune signaling. It is commonly used in research to study the impact of circadian regulation on metabolic and inflammatory diseases. SR-1114 is a valuable tool for exploring REV-ERBα function, aiding in the development of novel therapies for disorders such as obesity, type 2 diabetes, and chronic inflammation.