For research use only. Not for therapeutic Use.
SQ 29,548（Cat No.:I011764）is a potent and selective thromboxane A2 (TXA2) receptor antagonist that inhibits TXA2-mediated platelet aggregation and vasoconstriction. By blocking the TXA2 receptor (TP receptor), SQ 29,548 interferes with prostanoid signaling involved in thrombosis, inflammation, and cardiovascular disease. It is widely used in pharmacological research to study platelet function, vascular tone regulation, and the role of thromboxane signaling in pathophysiological processes. SQ 29,548 serves as a valuable tool for exploring anti-thrombotic strategies and understanding TXA2’s contribution to conditions such as atherosclerosis, stroke, and hypertension.
| CAS Number | 98672-91-4 |
| Synonyms | (Z)-7-[(1S,2R,3R,4R)-3-[[2-(phenylcarbamoyl)hydrazinyl]methyl]-7-oxabicyclo[2.2.1]heptan-2-yl]hept-5-enoic acid |
| Molecular Formula | C21H29N3O4 |
| Purity | ≥95% |
| IUPAC Name | (Z)-7-[(1S,2R,3R,4R)-3-[[2-(phenylcarbamoyl)hydrazinyl]methyl]-7-oxabicyclo[2.2.1]heptan-2-yl]hept-5-enoic acid |
| InChI | InChI=1S/C21H29N3O4/c25-20(26)11-7-2-1-6-10-16-17(19-13-12-18(16)28-19)14-22-24-21(27)23-15-8-4-3-5-9-15/h1,3-6,8-9,16-19,22H,2,7,10-14H2,(H,25,26)(H2,23,24,27)/b6-1-/t16-,17+,18+,19-/m1/s1 |
| InChIKey | RJNDVCNWVBWHLY-YVUOLYODSA-N |
| SMILES | C1C[C@@H]2[C@H]([C@H]([C@H]1O2)C/C=C\CCCC(=O)O)CNNC(=O)NC3=CC=CC=C3 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
