Spinorphin TFA

• CAT Number: I045814
• CAS Number: 2828433-21-0
• Molecular Formula: C47H65F3N8O12
• Molecular Weight: 991.06
• Purity: ≥95%
• Synonyms: (2S,3R)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-hydroxybutanoic acid;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C45H64N8O10.C2HF3O2/c1-23(2)19-31(46)39(56)50-37(25(5)6)43(60)51-36(24(3)4)42(59)49-34(20-27-14-16-29(55)17-15-27)44(61)53-18-10-13-35(53)41(58)48-33(40(57)52-38(26(7)54)45(62)63)21-28-22-47-32-12-9-8-11-30(28)32;3-2(4,5)1(6)7/h8-9,11-12,14-17,22-26,31,33-38,47,54-55H,10,13,18-21,46H2,1-7H3,(H,48,58)(H,49,59)(H,50,56)(H,51,60)(H,52,57)(H,62,63);(H,6,7)/t26-,31+,33+,34+,35+,36+,37+,38+;/m1./s1
• InChIKey: HGVNOCZYJWQUER-ZWRVRYFZSA-N
• SMILES: C[C@H]([C@@H](C(=O)O)NC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N)O.C(=O)(C(F)(F)F)O

Spinorphin TFA（Cat No.:I045814）is the trifluoroacetate salt of Spinorphin, an endogenous heptapeptide (Leu-Val-Val-Tyr-Pro-Trp-Thr) known for its potent antinociceptive and anti-inflammatory properties. It functions primarily as an inhibitor of enkephalin-degrading enzymes, thereby prolonging endogenous opioid activity, and also interacts with P2X3 and formyl peptide receptors. Spinorphin modulates pain perception, inflammation, and immune responses without the addictive potential of classical opioids. The TFA salt enhances peptide stability and handling, making Spinorphin TFA an important research tool in studies of pain modulation, neuroinflammation, and therapeutic approaches to non-opioid analgesia.