SPhos Pd G3

• CAT Number: R036976
• CAS Number: 1445085-82-4
• Molecular Formula: C40H51Cl2NO5PPdS-
• Molecular Weight: 866.20
• Purity: ≥95%
• Synonyms: (2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl) [2-(2′-Amino-1,1′-biphenyl)]palladium(II) Methanesulfonate; [2’-(Amino-κN)[1,1’-biphenyl]-2-yl-κC][dicyclohexyl(2’,6’-dimethoxy[1,1’-biphenyl]-2-yl)phosphine-κP](methanesulfonato-κO)palladium
• Storage: Store at +4C

SPhos Pd G3（Cat No.:R036976）is a third-generation palladium pre-catalyst featuring the bulky, electron-rich SPhos ligand. It is a highly active and air-stable complex used in cross-coupling reactions, including Suzuki-Miyaura, Buchwald-Hartwig amination, and related C–C and C–N bond-forming transformations. The SPhos ligand enhances reactivity with challenging aryl chlorides and sterically hindered substrates, providing excellent yields under mild conditions. Its pre-formed structure simplifies catalyst handling, minimizing the need for in situ activation. SPhos Pd G3 is widely employed in pharmaceutical synthesis, materials science, and fine chemical development for efficient and selective catalysis.