SP 600125, negative control- CAS 54642-23-8
CAS No.: 54642-23-8

PubChem Substance ID: 355426571

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Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:	R065996
Synonyms:	JNK Inhibitor II, negative control
Molecular Formula:	C15H10N2O
Molecular Weight:	234.258
Description:	SP 600125 (Item No. 10010466) is a selective, cell-permeable, reversible inhibitor of JNK isoforms 1-3 with Ki values of 0.19 μM.
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SP 600125 (Item No. 10010466) is a selective, cell-permeable, reversible inhibitor of JNK isoforms 1-3 with K_i values of 0.19 μM. SP 600125, negative control is a methylated analog of SP 600125 that has much lower affinity for JNK isoforms (IC₅₀s = 18 and 24 µM for JNK2 and JNK3, respectively).

Cat No:	R065996
Cas No:	54642-23-8
Product-Name:	SP 600125, negative control
InChI:	InChI=1S/C15H10N2O/c1-17-12-8-4-7-11-13(12)14(16-17)9-5-2-3-6-10(9)15(11)18/h2-8H,1H3
InChIKey:	ODZGYELAMAOARP-UHFFFAOYSA-N
SMILES:	CN1C2=CC=CC3=C2C(=N1)C4=CC=CC=C4C3=O

1.Bennett, B.L.,Sasaki, D.T.,Murray, B.W., et al. SP600125, an anthrapyrazolone inhibitor of jun N-terminal kinase. Proceedings of the National Academy of Sciences of the United States of America 98(24), 13681-13686 (2001).

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SP 600125, negative control- CAS 54642-23-8
CAS No.: 54642-23-8

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SP 600125, negative control- CAS 54642-23-8CAS No.: 54642-23-8

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SP 600125, negative control- CAS 54642-23-8
CAS No.: 54642-23-8