Soyasaponin II

• CAT Number: I045508
• CAS Number: 55319-36-3
• Molecular Formula: C47H76O17
• Molecular Weight: 913.10
• Purity: ≥95%
• Synonyms: (2S,3S,4S,5R,6R)-6-[[(3S,4S,4aR,6aR,6bS,8aR,9R,12aS,14aR,14bR)-9-hydroxy-4-(hydroxymethyl)-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-5-[(2S,3R,4S,5S)-4,5-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxyoxane-2-carboxylic acid
• InChI: InChI=1S/C47H76O17/c1-21-29(51)31(53)34(56)39(60-21)63-36-30(52)24(49)19-59-40(36)64-37-33(55)32(54)35(38(57)58)62-41(37)61-28-12-13-44(5)25(45(28,6)20-48)11-14-47(8)26(44)10-9-22-23-17-42(2,3)18-27(50)43(23,4)15-16-46(22,47)7/h9,21,23-37,39-41,48-56H,10-20H2,1-8H3,(H,57,58)/t21-,23-,24-,25+,26+,27+,28-,29-,30-,31+,32-,33-,34+,35-,36+,37+,39-,40-,41+,43+,44-,45+,46+,47+/m0/s1
• InChIKey: IBZLICPLPYSFNZ-IVWMTKFPSA-N
• SMILES: CC1C(C(C(C(O1)OC2C(C(COC2OC3C(C(C(OC3OC4CCC5(C(C4(C)CO)CCC6(C5CC=C7C6(CCC8(C7CC(CC8O)(C)C)C)C)C)C)C(=O)O)O)O)O)O)O)O)O

Soyasaponin II (Cat No.: I045508)is a triterpenoid saponin derived from soybeans (Glycine max), belonging to the oleanane-type saponins. It exhibits multiple bioactivities, including anticancer, anti-inflammatory, antioxidant, and cholesterol-lowering effects, making it highly relevant for metabolic and cardiovascular disease research. Soyasaponin II modulates signaling pathways linked to apoptosis, lipid metabolism, and immune responses, offering insights into therapeutic mechanisms. Its amphiphilic nature also contributes to membrane interactions and bioavailability studies, positioning it as a valuable compound for pharmacological, nutraceutical, and biomedical research applications.

Reference

[1]. Hayashi K, et al. Inhibitory activity of soyasaponin II on virus replication in vitro. Planta Med. 1997;63(2):102-105.
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[2]. Wang F, et al. Soyasaponin II protects against acute liver failure through diminishing YB-1 phosphorylation and Nlrp3-inflammasome priming in mice. Theranostics. 2020;10(6):2714-2726. Published 2020 Feb 3.
[Content Brief]