For research use only. Not for therapeutic Use.
Sovleplenib（Cat No.:I045094）is a selective spleen tyrosine kinase (Syk) inhibitor under investigation for the treatment of autoimmune and hematologic disorders. By blocking Syk-mediated signaling in B cells and myeloid cells, Sovleplenib reduces inflammatory cytokine production, immune complex-mediated responses, and abnormal cell proliferation. It is being evaluated for immune thrombocytopenia (ITP), B-cell malignancies, and other Syk-driven diseases. Sovleplenib’s oral bioavailability and targeted mechanism offer promise for improving patient outcomes with fewer off-target effects. Supplied for research in immune modulation, hematologic malignancies, and B-cell–mediated autoimmune conditions.
| CAS Number | 1415792-84-5 |
| Synonyms | 7-[4-(1-methylsulfonylpiperidin-4-yl)phenyl]-N-[[(2S)-morpholin-2-yl]methyl]pyrido[3,4-b]pyrazin-5-amine |
| Molecular Formula | C24H30N6O3S |
| Purity | ≥95% |
| IUPAC Name | 7-[4-(1-methylsulfonylpiperidin-4-yl)phenyl]-N-[[(2S)-morpholin-2-yl]methyl]pyrido[3,4-b]pyrazin-5-amine |
| InChI | InChI=1S/C24H30N6O3S/c1-34(31,32)30-11-6-18(7-12-30)17-2-4-19(5-3-17)21-14-22-23(27-9-8-26-22)24(29-21)28-16-20-15-25-10-13-33-20/h2-5,8-9,14,18,20,25H,6-7,10-13,15-16H2,1H3,(H,28,29)/t20-/m0/s1 |
| InChIKey | NJIAKNWTIVDSDA-FQEVSTJZSA-N |
| SMILES | CS(=O)(=O)N1CCC(CC1)C2=CC=C(C=C2)C3=CC4=NC=CN=C4C(=N3)NC[C@@H]5CNCCO5 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
