For research use only. Not for therapeutic Use.
Sodium camptothecin（Cat No.:R002151）is a water-soluble derivative of camptothecin, a natural alkaloid originally isolated from Camptotheca acuminata. It functions as a potent topoisomerase I inhibitor, interfering with DNA replication and transcription, leading to cancer cell death. This sodium salt form enhances camptothecin’s solubility and stability, improving its potential for clinical application. Sodium camptothecin exhibits strong antitumor activity against various cancers, including colon, lung, and ovarian cancers. It serves as a lead compound for the development of chemotherapeutic agents and remains important in cancer research and drug development efforts.
| CAS Number | 25387-67-1 |
| Synonyms | sodium;(2S)-2-hydroxy-2-[8-(hydroxymethyl)-9-oxo-11H-indolizino[1,2-b]quinolin-7-yl]butanoate |
| Molecular Formula | C20H17N2NaO5 |
| Purity | ≥95% |
| IUPAC Name | sodium;(2S)-2-hydroxy-2-[8-(hydroxymethyl)-9-oxo-11H-indolizino[1,2-b]quinolin-7-yl]butanoate |
| InChI | InChI=1S/C20H18N2O5.Na/c1-2-20(27,19(25)26)14-8-16-17-12(9-22(16)18(24)13(14)10-23)7-11-5-3-4-6-15(11)21-17;/h3-8,23,27H,2,9-10H2,1H3,(H,25,26);/q;+1/p-1/t20-;/m0./s1 |
| InChIKey | HPSUBMDJBRNXKK-BDQAORGHSA-M |
| SMILES | CC[C@](C1=C(C(=O)N2CC3=CC4=CC=CC=C4N=C3C2=C1)CO)(C(=O)[O-])O.[Na+] |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
