SNIPER(TACC3)-11

• CAT Number: I043850
• CAS Number: 2906151-68-4
• Molecular Formula: C51H66N10O7S2
• Molecular Weight: 995.26
• Purity: ≥95%
• Synonyms: N-[2-[2-[2-[3-[2-[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]pyrrolidin-2-yl]-1,3-thiazole-4-carbonyl]phenoxy]ethoxy]ethoxy]ethyl]-4-[4-[[[4-(2-methylpropylamino)pyrimidin-2-yl]amino]methyl]-1,3-thiazol-2-yl]benzamide
• InChI: InChI=1S/C51H66N10O7S2/c1-33(2)29-55-43-19-20-54-51(59-43)56-30-39-31-69-48(57-39)37-17-15-36(16-18-37)47(64)53-21-23-66-24-25-67-26-27-68-40-13-8-12-38(28-40)45(62)41-32-70-49(58-41)42-14-9-22-61(42)50(65)44(35-10-6-5-7-11-35)60-46(63)34(3)52-4/h8,12-13,15-20,28,31-35,42,44,52H,5-7,9-11,14,21-27,29-30H2,1-4H3,(H,53,64)(H,60,63)(H2,54,55,56,59)/t34-,42-,44-/m0/s1
• InChIKey: CTMIQTSKAZXRFZ-YSQZVTEJSA-N
• SMILES: C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C3=NC(=CS3)C(=O)C4=CC(=CC=C4)OCCOCCOCCNC(=O)C5=CC=C(C=C5)C6=NC(=CS6)CNC7=NC=CC(=N7)NCC(C)C)NC

SNIPER(TACC3)-11（Cat No.:I043850）is a selective small molecule designed to target and degrade the TACC3 (Transforming Acidic Coiled-Coil Containing Protein 3) protein through the proteasomal pathway. TACC3 is involved in mitotic spindle assembly and plays a key role in cell division and cancer cell proliferation. By recruiting the cellular machinery responsible for protein degradation, SNIPER(TACC3)-11 disrupts TACC3’s function, leading to cancer cell death. This compound has shown potential in the treatment of cancers where TACC3 is overexpressed, offering a novel approach to targeting tumor growth through targeted protein degradation.