SN-011（Cat No.:I028471）is a potent, selective inhibitor of the NLRP3 inflammasome, a multiprotein complex that activates caspase-1, leading to maturation of pro-inflammatory cytokines IL-1β and IL-18. By blocking NLRP3 activation, SN-011 reduces inflammation and pyroptotic cell death associated with autoimmune, metabolic, and neurodegenerative diseases. It demonstrates strong efficacy in preclinical models of inflammatory disorders, including gout, atherosclerosis, and Alzheimer’s disease. SN-011 is a valuable research tool for studying inflammasome biology and holds therapeutic potential for targeting NLRP3-driven pathologies while preserving host defense mechanisms against infections.