SMI-16a

  • CAT Number: I013451
  • CAS Number: 587852-28-6
  • Molecular Formula: C₁₃H₁₃NO₃S
  • Molecular Weight: 263.31
  • Purity: ≥95%
Inquiry Now

SMI-16a(Cat No.:I013451), is a chemical compound with significance in pharmacology and molecular biology research. It is often employed as an experimental tool in laboratories to study cellular processes and signaling pathways. While the specific mechanisms of SMI-16a may vary depending on the research context, it is generally known to affect various cellular functions, making it valuable in investigating the roles of specific molecular targets. By inhibiting or modulating these targets, SMI-16a contributes to our understanding of fundamental biological processes and may have potential applications in drug development or the development of novel therapies for specific diseases and conditions.

Catalog Number I013451
CAS Number 587852-28-6
Molecular Formula

C₁₃H₁₃NO₃S

Purity 95%
Target Pim
Solubility DMSO: ≥150 mg/mL
Storage 2-8°C(protect from light)
IUPAC Name (5E)-5-[(4-propoxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione
InChI InChI=1S/C13H13NO3S/c1-2-7-17-10-5-3-9(4-6-10)8-11-12(15)14-13(16)18-11/h3-6,8H,2,7H2,1H3,(H,14,15,16)/b11-8+
InChIKey GBWOSXZUTXXXQF-DHZHZOJOSA-N
SMILES CCCOC1=CC=C(C=C1)C=C2C(=O)NC(=O)S2
Reference

[1]. Xia Z, et al. Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases. J Med Chem. 2009 Jan 8;52(1):74-86.<br>[2]. Hiasa M, et al. Pim-2 kinase is an important target of treatment for tumor progression and bone loss in myeloma. Leukemia. 2015 Jan;29(1):207-17.

Request a Quote