For research use only. Not for therapeutic Use.
Sm4(CAT: M011079) is a selective SOX18 inhibitor that interferes with SOX18-DNA binding, effectively suppressing the transcriptional activity of SOX18 and other SoxF family members. By disrupting this transcriptional program, Sm4 impairs SOX18-driven gene expression both in vitro and in vivo, making it a valuable tool for studying the molecular mechanisms of angiogenesis, vascular development, and cancer metastasis. Sm4 has shown particular promise in preclinical models of vascular tumors and metastatic progression, where SOX18 plays a critical regulatory role. This compound supports targeted research into transcription factor modulation and the development of anti-metastatic and anti-angiogenic therapies.
| CAS Number | 365542-77-4 |
| Synonyms | 2-hydroxy-6-(2-naphthalen-2-ylethyl)benzoic acid |
| Molecular Formula | C19H16O3 |
| Purity | ≥95% |
| IUPAC Name | 2-hydroxy-6-(2-naphthalen-2-ylethyl)benzoic acid |
| InChI | InChI=1S/C19H16O3/c20-17-7-3-6-15(18(17)19(21)22)11-9-13-8-10-14-4-1-2-5-16(14)12-13/h1-8,10,12,20H,9,11H2,(H,21,22) |
| InChIKey | GGVFBUYNEPBFQT-UHFFFAOYSA-N |
| SMILES | C1=CC=C2C=C(C=CC2=C1)CCC3=C(C(=CC=C3)O)C(=O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
