For research use only. Not for therapeutic Use.
SKF 77434 hydrobromide(CAT: I010440) is a potent and selective dopamine D1 receptor antagonist, widely used in neuroscience research to study dopaminergic signaling and receptor function. By blocking D1 receptor activity, SKF 77434 hydrobromide enables detailed investigation of dopamine-related pathways involved in motor control, cognition, reward, and neuropsychiatric disorders such as schizophrenia and Parkinson’s disease. This compound is valuable for both in vitro and in vivo applications, offering consistent performance and high specificity. Supplied as a stable hydrobromide salt, SKF 77434 is an essential pharmacological tool for exploring central nervous system function and dopamine receptor modulation.
| CAS Number | 300561-58-4 |
| Synonyms | 5-phenyl-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol;hydrobromide |
| Molecular Formula | C19H22BrNO2 |
| Purity | ≥95% |
| IUPAC Name | 5-phenyl-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol;hydrobromide |
| InChI | InChI=1S/C19H21NO2.BrH/c1-2-9-20-10-8-15-11-18(21)19(22)12-16(15)17(13-20)14-6-4-3-5-7-14;/h2-7,11-12,17,21-22H,1,8-10,13H2;1H |
| InChIKey | JWQRAXTWDYUBFI-UHFFFAOYSA-N |
| SMILES | C=CCN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)O.Br |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
