For research use only. Not for therapeutic Use.
SK-575（Cat No.:I043721）is a potent small molecule inhibitor that targets the protein kinase CK2 (Casein Kinase 2), which plays a key role in regulating various cellular processes, including cell growth, survival, and differentiation. CK2 is often overexpressed in cancer cells and is involved in promoting tumorigenesis and resistance to apoptosis. By inhibiting CK2, SK-575 disrupts these pathways, potentially leading to reduced cancer cell proliferation and enhanced sensitivity to chemotherapy. SK-575 is being explored as a therapeutic agent in oncology, offering a novel strategy to target CK2-driven cancers and improve treatment outcomes.
| CAS Number | 2523016-96-6 |
| Synonyms | N-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethyl]-12-[4-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]piperazin-1-yl]-12-oxododecanamide |
| Molecular Formula | C47H53FN8O8 |
| Purity | ≥95% |
| IUPAC Name | N-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethyl]-12-[4-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]piperazin-1-yl]-12-oxododecanamide |
| InChI | InChI=1S/C47H53FN8O8/c48-35-19-18-30(29-37-31-12-9-10-13-32(31)43(60)53-52-37)28-34(35)45(62)55-26-24-54(25-27-55)41(59)17-8-6-4-2-1-3-5-7-16-39(57)50-23-22-49-36-15-11-14-33-42(36)47(64)56(46(33)63)38-20-21-40(58)51-44(38)61/h9-15,18-19,28,38,49H,1-8,16-17,20-27,29H2,(H,50,57)(H,53,60)(H,51,58,61) |
| InChIKey | HPBWDZVXFSTVMR-UHFFFAOYSA-N |
| SMILES | C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCNC(=O)CCCCCCCCCCC(=O)N4CCN(CC4)C(=O)C5=C(C=CC(=C5)CC6=NNC(=O)C7=CC=CC=C76)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
