For research use only. Not for therapeutic Use.
Sipagladenant（Cat No.:I043365）is an oral, selective antagonist of the A2A adenosine receptor, which plays a critical role in regulating immune responses, inflammation, and cell signaling. By blocking this receptor, Sipagladenant aims to modulate the immune system and reduce inflammatory responses. It has been investigated for its potential therapeutic applications in conditions such as cancer, where immune suppression enables tumor progression, and in inflammatory diseases like rheumatoid arthritis. Sipagladenant’s ability to target the A2A receptor makes it a promising candidate for therapies aimed at enhancing immune function and reducing chronic inflammation.
| CAS Number | 858979-50-7 |
| Synonyms | N-[4-(furan-2-yl)-5-(oxane-4-carbonyl)-1,3-thiazol-2-yl]-6-methylpyridine-3-carboxamide |
| Molecular Formula | C20H19N3O4S |
| Purity | ≥95% |
| IUPAC Name | N-[4-(furan-2-yl)-5-(oxane-4-carbonyl)-1,3-thiazol-2-yl]-6-methylpyridine-3-carboxamide |
| InChI | InChI=1S/C20H19N3O4S/c1-12-4-5-14(11-21-12)19(25)23-20-22-16(15-3-2-8-27-15)18(28-20)17(24)13-6-9-26-10-7-13/h2-5,8,11,13H,6-7,9-10H2,1H3,(H,22,23,25) |
| InChIKey | KMFLQPJJHQNKKF-UHFFFAOYSA-N |
| SMILES | CC1=NC=C(C=C1)C(=O)NC2=NC(=C(S2)C(=O)C3CCOCC3)C4=CC=CO4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
