Sildenafil-d3N-1

• CAT Number: I040593
• CAS Number: 1126745-87-6
• CAS(unlabeled): 139755-83-2
• Molecular Formula: C22H27D3N6O4S
• Molecular Weight: 477.59
• Purity: ≥95%
• Synonyms: 1-methyl-3-propyl-5-[2,4,5-trideuterio-6-ethoxy-3-(4-methylpiperazin-1-yl)sulfonylphenyl]-6H-pyrazolo[4,3-d]pyrimidin-7-one
• InChI: InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)/i8D,9D,14D
• InChIKey: BNRNXUUZRGQAQC-YWZPVOOSSA-N
• SMILES: [2H]C1=C(C(=C(C(=C1OCC)C2=NC3=C(C(=O)N2)N(N=C3CCC)C)[2H])S(=O)(=O)N4CCN(CC4)C)[2H]

Sildenafil-d₃N-1(CAT: I040593) is a deuterium-labeled analog of Sildenafil, featuring three stable deuterium atoms incorporated for use as an internal standard in quantitative LC-MS/MS analysis. This isotopically labeled compound retains the pharmacological and physicochemical properties of its parent molecule, making it ideal for accurate bioanalytical studies, pharmacokinetics, and metabolic profiling. It supports sensitive detection and reliable quantification of Sildenafil in complex biological matrices. Sildenafil-d₃N-1 is commonly employed in clinical and forensic research settings to ensure data precision and reproducibility in drug monitoring and therapeutic studies involving phosphodiesterase type 5 (PDE5) inhibitors.