Sigma-LIGAND-1 hydrochloride

• CAT Number: M117436
• CAS Number: 139652-86-1
• Molecular Formula: C27H34ClNO4
• Molecular Weight: 472.02
• Purity: ≥95%
• Synonyms: 6-[6-(4-hydroxypiperidin-1-yl)hexoxy]-3-methyl-2-phenylchromen-4-one;hydrochloride
• InChI: InChI=1S/C27H33NO4.ClH/c1-20-26(30)24-19-23(11-12-25(24)32-27(20)21-9-5-4-6-10-21)31-18-8-3-2-7-15-28-16-13-22(29)14-17-28;/h4-6,9-12,19,22,29H,2-3,7-8,13-18H2,1H3;1H
• InChIKey: GWSBQIZSTCDSLE-UHFFFAOYSA-N
• SMILES: CC1=C(OC2=C(C1=O)C=C(C=C2)OCCCCCCN3CCC(CC3)O)C4=CC=CC=C4.Cl

Sigma-LIGAND-1 hydrochloride（Cat No.:M117436）is a selective, high-affinity agonist targeting sigma-1 receptors, integral membrane proteins implicated in numerous physiological processes, including neuroprotection, cognition, mood regulation, and cell survival. By modulating sigma-1 receptor activity, Sigma-LIGAND-1 hydrochloride exerts protective effects against neuronal damage, reduces oxidative stress, and supports cellular homeostasis. Its pharmacological profile makes it particularly valuable in investigating treatments for neurodegenerative diseases, psychiatric disorders, and neuropathic pain. Researchers frequently utilize Sigma-LIGAND-1 hydrochloride to elucidate receptor function, signaling mechanisms, and therapeutic potential, enhancing understanding of sigma-1 mediated neurobiology and pathology.