For research use only. Not for therapeutic Use.
SH-42（Cat No.:I044064）is a selective inhibitor of soluble epoxide hydrolase (sEH), an enzyme that metabolizes epoxyeicosatrienoic acids (EETs), which are lipid signaling molecules involved in inflammation, pain regulation, and cardiovascular function. By inhibiting sEH, SH-42 stabilizes EET levels, exerting anti-inflammatory and vasodilatory effects. It has been studied in preclinical models for its therapeutic potential in hypertension, inflammation, and neurodegenerative disorders. SH-42 is a valuable compound in pharmacological research for probing the role of sEH and exploring its inhibition as a strategy for treating chronic inflammatory and cardiovascular diseases.
| CAS Number | 2143952-36-5 |
| Synonyms | [(3S,5S,9R,10S,13R,14R,17R)-17-[(2S)-1-formyloxypropan-2-yl]-10,13-dimethyl-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate |
| Molecular Formula | C25H38O4 |
| Purity | ≥95% |
| IUPAC Name | [(3S,5S,9R,10S,13R,14R,17R)-17-[(2S)-1-formyloxypropan-2-yl]-10,13-dimethyl-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate |
| InChI | InChI=1S/C25H38O4/c1-16(14-28-15-26)21-7-8-22-20-6-5-18-13-19(29-17(2)27)9-11-24(18,3)23(20)10-12-25(21,22)4/h6,15-16,18-19,21-23H,5,7-14H2,1-4H3/t16-,18+,19+,21-,22+,23+,24+,25-/m1/s1 |
| InChIKey | ZMSGAXSBKXUQKY-PUCUFLQQSA-N |
| SMILES | C[C@H](COC=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3C2=CC[C@@H]4[C@@]3(CC[C@@H](C4)OC(=O)C)C)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
