Sermorelin(CAT: I009442), also known as GHRH (1-29), is a growth hormone-releasing hormone (GHRH) analog used as a diagnostic agent. It is a 29-amino acid polypeptide representing the 1–29 fragment from endogenous human GHRH and is thought to be the shortest fully functional fragment of GHRH. This product is used for medical research and development and other scientific research purposes.
| Catalog Number | I009442 |
| CAS Number | 114466-38-5 (acetate); 86168-78-7 (free base). |
| Synonyms | GHRH (1-29); Sermorelin acetate; trade name: Geref.;H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2 |
| Molecular Formula | C151H250N44O44S |
| Purity | 95% |
| Solubility | Soluble in DMSO, not in water |
| Storage | 0 - 4 °C for short term, or -20 °C for long term |
| SMILES | CC[C@@H]([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCCNC(N)=N)=O)CO)=O)C |
| Reference | </br> 1:Knoop A, Thomas A, Fichant E, Delahaut P, Schänzer W, Thevis M. Qualitative identification of growth hormone-releasing hormones in human plasma by means of immunoaffinity purification and LC-HRMS/MS. Anal Bioanal Chem. 2016 May;408(12):3145-53. doi: 10.1007/s00216-016-9377-3. Epub 2016 Feb 15. PubMed PMID: 26879649; PubMed Central PMCID: PMC4830873.</br> 2: Venhuis BJ, Keizers PH, Klausmann R, Hegger I. Operation resistance: A snapshot of falsified antibiotics and biopharmaceutical injectables in Europe. Drug Test Anal. 2016 Mar;8(3-4):398-401. doi: 10.1002/dta.1888. Epub 2015 Oct 12. PubMed PMID: 26456392. |
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