Segphos

• CAT Number: L034265
• CAS Number: 210169-54-3
• Molecular Formula: C38H28O4P2
• Molecular Weight: 610.60
• Purity: ≥95%
• IUPAC Name: [4-(5-diphenylphosphanyl-1,3-benzodioxol-4-yl)-1,3-benzodioxol-5-yl]-diphenylphosphane
• InChI: InChI=1S/C38H28O4P2/c1-5-13-27(14-6-1)43(28-15-7-2-8-16-28)33-23-21-31-37(41-25-39-31)35(33)36-34(24-22-32-38(36)42-26-40-32)44(29-17-9-3-10-18-29)30-19-11-4-12-20-30/h1-24H,25-26H2
• InChIKey: RZZDRSHFIVOQAF-UHFFFAOYSA-N
• SMILES: C1OC2=C(O1)C(=C(C=C2)P(C3=CC=CC=C3)C4=CC=CC=C4)C5=C(C=CC6=C5OCO6)P(C7=CC=CC=C7)C8=CC=CC=C8

Segphos（Cat No.:L034265）is a chiral diphosphine ligand widely used in asymmetric catalysis, particularly in transition metal-catalyzed reactions such as hydrogenation, allylic substitution, and cross-coupling. Structurally, it consists of a biaryl backbone with two phosphine groups positioned to create a well-defined chiral environment around the metal center. Developed by Takasago, Segphos and its derivatives (e.g., DM-Segphos, DTBM-Segphos) are known for their high enantioselectivity and efficiency in a broad range of catalytic transformations. It plays a critical role in synthesizing chiral pharmaceuticals, agrochemicals, and fine chemicals with precise stereochemical control.