For research use only. Not for therapeutic Use.
SDH-IN-1（Cat No.:I044093）is a potent and selective inhibitor of succinate dehydrogenase (SDH), also known as complex II of the mitochondrial electron transport chain and a key enzyme in the tricarboxylic acid (TCA) cycle. By blocking SDH activity, SDH-IN-1 disrupts mitochondrial respiration and alters cellular energy metabolism, making it valuable in studies of cancer metabolism, ischemia, and neurodegenerative diseases. It is also used to explore the role of succinate accumulation in driving inflammation and hypoxia signaling. SDH-IN-1 is a critical tool in metabolic research and mitochondria-targeted drug discovery.
| CAS Number | 2685795-52-0 |
| Synonyms | N-[(3,4-dichlorophenyl)methyl]-5-thiophen-2-yl-1,3,4-oxadiazole-2-carboxamide |
| Molecular Formula | C14H9Cl2N3O2S |
| Purity | ≥95% |
| IUPAC Name | N-[(3,4-dichlorophenyl)methyl]-5-thiophen-2-yl-1,3,4-oxadiazole-2-carboxamide |
| InChI | InChI=1S/C14H9Cl2N3O2S/c15-9-4-3-8(6-10(9)16)7-17-12(20)14-19-18-13(21-14)11-2-1-5-22-11/h1-6H,7H2,(H,17,20) |
| InChIKey | VHRCPMTYUKLSDU-UHFFFAOYSA-N |
| SMILES | C1=CSC(=C1)C2=NN=C(O2)C(=O)NCC3=CC(=C(C=C3)Cl)Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
