For research use only. Not for therapeutic Use.
SCR130（Cat No.:I044427）is a selective small-molecule inhibitor targeting the interaction between Signal Transducer and Activator of Transcription 3 (STAT3) and its phosphotyrosine-containing binding partners. By disrupting STAT3 dimerization and nuclear translocation, SCR130 effectively blocks transcriptional activation of genes involved in cell proliferation, survival, and immune evasion. It is especially valuable in cancer research, where aberrant STAT3 signaling drives tumor progression and resistance to therapy. SCR130 has demonstrated antitumor activity in preclinical models and is used to explore the therapeutic potential of STAT3 inhibition in oncology and inflammatory disease contexts.
| CAS Number | 2377858-38-1 |
| Synonyms | 2,4-bis(4-chlorophenyl)-8-sulfanylidene-1,7,9-triazaspiro[4.5]dec-1-ene-6,10-dione |
| Molecular Formula | C19H13Cl2N3O2S |
| Purity | ≥95% |
| IUPAC Name | 2,4-bis(4-chlorophenyl)-8-sulfanylidene-1,7,9-triazaspiro[4.5]dec-1-ene-6,10-dione |
| InChI | InChI=1S/C19H13Cl2N3O2S/c20-12-5-1-10(2-6-12)14-9-15(11-3-7-13(21)8-4-11)24-19(14)16(25)22-18(27)23-17(19)26/h1-8,14H,9H2,(H2,22,23,25,26,27) |
| InChIKey | QEMQLCCYJLGAKB-UHFFFAOYSA-N |
| SMILES | C1C(C2(C(=O)NC(=S)NC2=O)N=C1C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
