For research use only. Not for therapeutic Use.
SCP1-IN-1(Cat No.:I044085)is a potent and selective inhibitor of small C-terminal domain phosphatase 1 (SCP1), an enzyme that dephosphorylates the C-terminal domain of RNA polymerase II, thereby regulating transcriptional elongation and gene expression. By targeting SCP1, this compound influences key transcriptional programs involved in neuronal differentiation, development, and epigenetic control. SCP1-IN-1 is a valuable tool for exploring the role of Ser5 and Ser7 dephosphorylation in transcription regulation and for studying neural-specific gene expression pathways. It is particularly useful in neurobiology and transcriptional research for dissecting phosphatase-mediated regulatory mechanisms.
CAS Number | 2764615-55-4 |
Synonyms | 1,1-dioxo-N-[2-[2-[[4-(trifluoromethoxy)phenyl]sulfonylamino]ethoxy]ethyl]-1-benzothiophene-2-carboxamide |
Molecular Formula | C20H19F3N2O7S2 |
Purity | ≥95% |
IUPAC Name | 1,1-dioxo-N-[2-[2-[[4-(trifluoromethoxy)phenyl]sulfonylamino]ethoxy]ethyl]-1-benzothiophene-2-carboxamide |
InChI | InChI=1S/C20H19F3N2O7S2/c21-20(22,23)32-15-5-7-16(8-6-15)34(29,30)25-10-12-31-11-9-24-19(26)18-13-14-3-1-2-4-17(14)33(18,27)28/h1-8,13,25H,9-12H2,(H,24,26) |
InChIKey | LOPHIWMZIIGDGK-UHFFFAOYSA-N |
SMILES | C1=CC=C2C(=C1)C=C(S2(=O)=O)C(=O)NCCOCCNS(=O)(=O)C3=CC=C(C=C3)OC(F)(F)F |
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