For research use only. Not for therapeutic Use.
SCH 51344（Cat No.:R029161）is a synthetic small-molecule compound known for its inhibitory activity against the Ras signaling pathway, which is frequently dysregulated in various cancers. It was initially identified as a Ras function inhibitor capable of disrupting Ras-dependent cell transformation and proliferation. SCH 51344 has been used in research to explore oncogenic Ras signaling, particularly its interactions with downstream effectors like Raf and PI3K. Though not developed for clinical use, it remains a valuable tool in cancer biology for studying Ras-driven tumorigenesis and testing targeted therapeutic strategies aimed at Ras or its associated pathways.
| CAS Number | 171927-40-5 |
| Synonyms | 2-[2-[(6-methoxy-3-methyl-2H-pyrazolo[3,4-b]quinolin-4-yl)amino]ethoxy]ethanol |
| Molecular Formula | C16H20N4O3 |
| Purity | ≥95% |
| IUPAC Name | 2-[2-[(6-methoxy-3-methyl-2H-pyrazolo[3,4-b]quinolin-4-yl)amino]ethoxy]ethanol |
| InChI | InChI=1S/C16H20N4O3/c1-10-14-15(17-5-7-23-8-6-21)12-9-11(22-2)3-4-13(12)18-16(14)20-19-10/h3-4,9,21H,5-8H2,1-2H3,(H2,17,18,19,20) |
| InChIKey | YWEGXZZAORIRQR-UHFFFAOYSA-N |
| SMILES | CC1=C2C(=C3C=C(C=CC3=NC2=NN1)OC)NCCOCCO |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
