For research use only. Not for therapeutic Use.
SCD1 inhibitor-3（Cat No.:I044450）is a selective small-molecule inhibitor of stearoyl-CoA desaturase 1 (SCD1), an essential enzyme that catalyzes the conversion of saturated fatty acids into monounsaturated fatty acids, key components of membrane lipids and signaling molecules. By blocking SCD1 activity, this inhibitor disrupts lipid metabolism, leading to reduced cell proliferation and increased apoptosis—particularly in cancer cells reliant on lipid synthesis. SCD1 inhibitor-3 is valuable in research on metabolic disorders, obesity, cancer, and non-alcoholic fatty liver disease (NAFLD), supporting therapeutic strategies targeting lipid biosynthesis and metabolic reprogramming.
| CAS Number | 1282606-48-7 |
| Synonyms | 3-[1-[(4-fluorophenyl)methyl]-5-oxo-1,2,4-triazol-4-yl]-N-(pyridin-3-ylmethyl)-1H-pyrazole-5-carboxamide |
| Molecular Formula | C19H16FN7O2 |
| Purity | ≥95% |
| IUPAC Name | 3-[1-[(4-fluorophenyl)methyl]-5-oxo-1,2,4-triazol-4-yl]-N-(pyridin-3-ylmethyl)-1H-pyrazole-5-carboxamide |
| InChI | InChI=1S/C19H16FN7O2/c20-15-5-3-13(4-6-15)11-27-19(29)26(12-23-27)17-8-16(24-25-17)18(28)22-10-14-2-1-7-21-9-14/h1-9,12H,10-11H2,(H,22,28)(H,24,25) |
| InChIKey | FAIXKYSRYKWWGK-UHFFFAOYSA-N |
| SMILES | C1=CC(=CN=C1)CNC(=O)C2=CC(=NN2)N3C=NN(C3=O)CC4=CC=C(C=C4)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
