SC99- CAS 882290-02-0
SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes, including Bcl-2, Bcl-xL, VEGF, cyclin D2, and E2F-1.
Catalog Number: I036098
CAS Number: 882290-02-0
Molecular Formula: C15H8Cl2FN3O
Molecular Weight:336.15
Purity: 98.0%
Appearance:Solid powder
* For research use only. Not for human or veterinary use.
Synonym
| Synonyms | SC99; SC-99; SC 99 |
|---|
Property
| Molecular Formula: | C15H8Cl2FN3O |
|---|---|
| Molecular Weight | 336.15 |
| Solubility | Soluble in DMSO |
| Purity | 98.0% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Computed Descriptor
| IUPAC Name | 2-(2-(3-Chloro-4-fluorophenyl)hydrazono)-3-(4-chlorophenyl)-3-oxo-propanenitrile |
|---|---|
| InChI | InChI=1S/C15H8Cl2FN3O/c16-10-3-1-9(2-4-10)15(22)14(8-19)21-20-11-5-6-13(18)12(17)7-11/h1-7,20H/b21-14+ |
| InChIKey | ZKULFSMYRSFHKE-KGENOOAVSA-N |
| SMILES | N#C/C(C(C1=CC=C(Cl)C=C1)=O)=NNC2=CC=C(F)C(Cl)=C2 |