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SC99 - CAS 882290-02-0

SC99（Cat No.:I036098） is a selective inhibitor of JAK2-STAT3 activation, a signaling pathway involved in cell proliferation and survival. By targeting this pathway, SC99 downregulates the expression of several genes modulated by STAT3, including Bcl-2, Bcl-xL, VEGF, cyclin D2, and E2F-1. This inhibition has potential therapeutic implications in various diseases characterized by dysregulated JAK2-STAT3 signaling, such as cancer.

Catalog Number: I036098

CAS Number: 882290-02-0

Molecular Formula: C15H8Cl2FN3O

Molecular Weight:336.15

Purity: 98.0%

Appearance:Solid powder

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* For research use only. Not for human or veterinary use.

Synonym

SynonymsSC99; SC-99; SC 99

Property

Molecular Formula: C15H8Cl2FN3O
Molecular Weight336.15
SolubilitySoluble in DMSO
Purity98.0%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Computed Descriptor

IUPAC Name2-(2-(3-Chloro-4-fluorophenyl)hydrazono)-3-(4-chlorophenyl)-3-oxo-propanenitrile
InChIInChI=1S/C15H8Cl2FN3O/c16-10-3-1-9(2-4-10)15(22)14(8-19)21-20-11-5-6-13(18)12(17)7-11/h1-7,20H/b21-14+
InChIKeyZKULFSMYRSFHKE-KGENOOAVSA-N
SMILESN#C/C(C(C1=CC=C(Cl)C=C1)=O)=NNC2=CC=C(F)C(Cl)=C2