SC209

For research use only. Not for therapeutic Use.

  • CAT Number: I044029
  • CAS Number: 1977557-86-0
  • Molecular Formula: C27H44N4O4
  • Molecular Weight: 488.66
  • Purity: ≥95%
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SC209(Cat No.:I044029)is a potent and selective antagonist of the serotonin 5-HT2B receptor, part of the G protein-coupled receptor family involved in neurotransmission, cardiovascular regulation, and fibrotic processes. By inhibiting 5-HT2B signaling, SC209 modulates serotonin-mediated effects, making it a valuable tool in research on cardiac valvulopathy, pulmonary hypertension, and neuropsychiatric disorders. Its specificity allows for targeted studies without affecting other serotonin receptor subtypes, reducing off-target effects. SC209 is particularly useful in dissecting the role of 5-HT2B in serotonin-related pathologies and evaluating therapeutic strategies aimed at serotonin receptor modulation.


CAS Number 1977557-86-0
Synonyms

(E,4S)-4-[[(2S)-2-[[(2S)-3-(3-aminophenyl)-3-methyl-2-(methylamino)butanoyl]amino]-3,3-dimethylbutanoyl]-methylamino]-2,5-dimethylhex-2-enoic acid

Molecular Formula C27H44N4O4
Purity ≥95%
IUPAC Name (E,4S)-4-[[(2S)-2-[[(2S)-3-(3-aminophenyl)-3-methyl-2-(methylamino)butanoyl]amino]-3,3-dimethylbutanoyl]-methylamino]-2,5-dimethylhex-2-enoic acid
InChI InChI=1S/C27H44N4O4/c1-16(2)20(14-17(3)25(34)35)31(10)24(33)22(26(4,5)6)30-23(32)21(29-9)27(7,8)18-12-11-13-19(28)15-18/h11-16,20-22,29H,28H2,1-10H3,(H,30,32)(H,34,35)/b17-14+/t20-,21-,22-/m1/s1
InChIKey ILRXQTICSGMLFH-ZYRIPLEJSA-N
SMILES CC(C)[C@@H](/C=C(\C)/C(=O)O)N(C)C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C(C)(C)C1=CC(=CC=C1)N)NC
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