For research use only. Not for therapeutic Use.
SBI-993 (Cat No.: I045517) is a potent and selective agonist of GPR84, a medium-chain fatty acid–sensing G protein-coupled receptor implicated in immune regulation and inflammation. Activation of GPR84 by SBI-993 promotes pro-inflammatory signaling in macrophages and other immune cells, making it a valuable probe for studying innate immunity and inflammatory diseases. Researchers use SBI-993 to investigate metabolic–immune interactions, GPCR pharmacology, and therapeutic strategies for conditions such as fibrosis, autoimmune disorders, and metabolic inflammation. Its specificity provides a reliable tool for immunology research.
| CAS Number | 2073059-82-0 |
| Synonyms | N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-4-[(2-morpholin-4-yl-2-oxoethyl)amino]benzamide |
| Molecular Formula | C23H24N4O4S |
| Purity | ≥95% |
| InChI | InChI=1S/C23H24N4O4S/c1-30-19-8-4-16(5-9-19)20-15-32-23(25-20)26-22(29)17-2-6-18(7-3-17)24-14-21(28)27-10-12-31-13-11-27/h2-9,15,24H,10-14H2,1H3,(H,25,26,29) |
| InChIKey | BMMQYFWEGRLMNT-UHFFFAOYSA-N |
| SMILES | COC1=CC=C(C=C1)C2=CSC(=N2)NC(=O)C3=CC=C(C=C3)NCC(=O)N4CCOCC4 |
| Reference | [1]. Byungyong Ahn, et al. MondoA coordinately regulates skeletal myocyte lipid homeostasis and insulin signaling. J Clin Invest. 2016 Sep 1;126(9):3567-79. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
