Sarilumab

• CAT Number: I045817
• CAS Number: 1189541-98-7
• Purity: ≥95%

Sarilumab（Cat No.:I045817）is a fully human monoclonal antibody that targets the interleukin-6 receptor (IL-6R), blocking IL-6–mediated pro-inflammatory signaling. It is approved for the treatment of moderate-to-severe rheumatoid arthritis in patients who have had an inadequate response to disease-modifying antirheumatic drugs (DMARDs). By inhibiting IL-6 activity, sarilumab reduces inflammation, joint damage, and associated symptoms. It is administered subcutaneously and has been investigated in other inflammatory and autoimmune conditions. Sarilumab represents an important biologic therapy in immunology, offering targeted intervention for chronic inflammatory disease management.