Sarecycline HCl

  • CAT Number: I009292
  • CAS Number: 1035979-44-2 (HCl); 1035654-66-0 (frtee base)
  • Molecular Formula: C24H30ClN3O8
  • Molecular Weight: 523.967
  • Purity: ≥95%
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Sarecycline(CAT: I009292), also known as WC-3035 and P005672, is a novel, tetracycline-derived, narrow-spectrum antibiotic being developed for use as an antibiotic treatment for patients suffering from moderate to severe acne vulgaris. Sarecycline was designed by Paratek as a narrow-spectrum antibiotic with anti-inflammatory activity and the potential for a favorable tolerability profile.

Catalog Number I009292
CAS Number 1035979-44-2 (HCl); 1035654-66-0 (frtee base)
Synonyms

P005672; P-005672; P 005672; P005672 HCl; Sarecycline hydrochloride;(4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-7-((methoxy(methyl)amino)methyl)-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride

Molecular Formula

C24H30ClN3O8

Purity 95%
Solubility Soluble in DMSO, not in water
Storage 0 - 4 °C for short term, or -20 °C for long term
SMILES O=C(C1=C(O)[C@@H](N(C)C)[C@@](C[C@@]2([H])C(C(C3=C(O)C=CC(CN(OC)C)=C3C2)=O)=C4O)([H])[C@@]4(O)C1=O)N.[H]Cl
Reference

<br />
Karpiuk I, Tyski S. Looking for new preparations for antibacterial therapy. IV. New antimicrobial agents from the aminoglycoside, macrolide and tetracycline groups in clinical trials. Przegl Epidemiol. 2015;69(4):723-9, 865-70. English, Polish. PubMed PMID: 27139351.

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