Saralasin TFA

• CAT Number: I045863
• Molecular Formula: C44H66F3N13O12
• Molecular Weight: 1026.07
• Purity: ≥95%
• Synonyms: (2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]propanoic acid;2,2,2-trifluoroacetic acid
• InChI: InChI=1S/C42H65N13O10.C2HF3O2/c1-22(2)33(53-35(58)28(50-32(57)20-45-6)9-7-15-47-42(43)44)38(61)51-29(17-25-11-13-27(56)14-12-25)36(59)54-34(23(3)4)39(62)52-30(18-26-19-46-21-48-26)40(63)55-16-8-10-31(55)37(60)49-24(5)41(64)65;3-2(4,5)1(6)7/h11-14,19,21-24,28-31,33-34,45,56H,7-10,15-18,20H2,1-6H3,(H,46,48)(H,49,60)(H,50,57)(H,51,61)(H,52,62)(H,53,58)(H,54,59)(H,64,65)(H4,43,44,47);(H,6,7)/t24-,28-,29-,30-,31-,33-,34-;/m0./s1
• InChIKey: MSJJUBUOJZCFIK-LYHTUURTSA-N
• SMILES: C[C@@H](C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC2=CN=CN2)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)CNC.C(=O)(C(F)(F)F)O

Saralasin TFA（Cat No.:I045863）is the trifluoroacetate salt form of saralasin, a synthetic peptide and competitive angiotensin II receptor antagonist. Structurally derived from angiotensin II, it retains receptor-binding affinity but lacks full agonist activity, enabling it to block vasoconstrictive and hypertensive effects of angiotensin II. Saralasin TFA has been used experimentally to study the renin–angiotensin system, cardiovascular regulation, and hypertension pathophysiology. Though not developed into a therapeutic drug, it remains an important pharmacological tool in cardiovascular and renal research for probing angiotensin receptor function and signaling mechanisms.