Saikosaponin B3

• CAT Number: I018460
• CAS Number: 58316-42-0
• Molecular Formula: C43H72O14
• Molecular Weight: 813.02
• Purity: ≥95%
• Synonyms: (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,4R,4aR,6aR,6bS,8S,8aS,12aS,14R,14aR,14bS)-8-hydroxy-4,8a-bis(hydroxymethyl)-14-methoxy-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3,5-dihydroxy-6-methyloxan-4-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
• InChI: InChI=1S/C43H72O14/c1-21-29(48)34(57-36-32(51)31(50)30(49)25(18-44)55-36)33(52)37(54-21)56-28-10-11-39(4)26(40(28,5)19-45)9-12-41(6)35(39)24(53-8)15-22-23-16-38(2,3)13-14-43(23,20-46)27(47)17-42(22,41)7/h15,21,23-37,44-52H,9-14,16-20H2,1-8H3/t21-,23+,24-,25-,26-,27+,28+,29+,30-,31+,32-,33-,34+,35-,36+,37+,39+,40+,41-,42-,43-/m1/s1
• InChIKey: GLQYFMRUYWFXGT-ZGFARVGISA-N
• SMILES: C[C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@H]2CC[C@]3([C@H]([C@]2(C)CO)CC[C@@]4([C@@H]3[C@@H](C=C5[C@]4(C[C@@H]([C@@]6([C@H]5CC(CC6)(C)C)CO)O)C)OC)C)C)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)O

Saikosaponin B3（Cat  No.:I018460）is a triterpenoid saponin isolated from Bupleurum species, plants long used in traditional Chinese medicine. Structurally, it belongs to the oleanane-type saponins, featuring a triterpene backbone linked to sugar moieties that enhance solubility and biological activity. Research demonstrates that Saikosaponin B3 possesses anti-inflammatory, immunomodulatory, and hepatoprotective effects, along with potential anticancer properties. It has been studied for roles in regulating oxidative stress, apoptosis, and immune signaling pathways. These activities make Saikosaponin B3 a valuable compound for pharmacological, biochemical, and natural product research.