For research use only. Not for therapeutic Use.
SAG Dihydrochloride（Cat No.:I044334）is a potent small-molecule agonist of the Smoothened (SMO) receptor, a key component of the Hedgehog (Hh) signaling pathway. By activating SMO, SAG stimulates downstream signaling involved in embryonic development, stem cell maintenance, and tissue regeneration. It is widely used in developmental biology and cancer research to investigate Hh pathway dynamics and therapeutic modulation. The dihydrochloride form improves solubility for in vitro and in vivo applications. SAG Dihydrochloride is a valuable tool for probing Hh-related mechanisms and exploring regenerative medicine and oncogenic signaling models.
| CAS Number | 2702366-44-5 |
| Synonyms | 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide;dihydrochloride |
| Molecular Formula | C28H30Cl3N3OS |
| Purity | ≥95% |
| IUPAC Name | 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide;dihydrochloride |
| InChI | InChI=1S/C28H28ClN3OS.2ClH/c1-30-22-9-11-23(12-10-22)32(28(33)27-26(29)24-7-2-3-8-25(24)34-27)18-19-5-4-6-21(17-19)20-13-15-31-16-14-20;;/h2-8,13-17,22-23,30H,9-12,18H2,1H3;2*1H |
| InChIKey | SWBYSYANHQTINY-UHFFFAOYSA-N |
| SMILES | CNC1CCC(CC1)N(CC2=CC(=CC=C2)C3=CC=NC=C3)C(=O)C4=C(C5=CC=CC=C5S4)Cl.Cl.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
