For research use only. Not for therapeutic Use.
(S)-TXNIP-IN-1（Cat No.:I015556）is a selective small-molecule inhibitor of thioredoxin-interacting protein (TXNIP), a regulator of cellular redox balance, glucose metabolism, and inflammation. By blocking TXNIP, this compound helps reduce oxidative stress and modulate metabolic signaling pathways linked to diabetes, cardiovascular dysfunction, and neurodegeneration. Preclinical studies suggest it may protect against β-cell apoptosis, improve insulin sensitivity, and mitigate inflammatory damage. As a research tool, (S)-TXNIP-IN-1 is valuable for investigating redox biology, metabolic disease mechanisms, and therapeutic strategies targeting oxidative stress–driven pathologies across multiple disease areas.
| CAS Number | 1212421-96-9 |
| Synonyms | (2S)-2-(1,3-dioxopyrrolo[3,4-c]pyridin-2-yl)-3-methylbutanoic acid |
| Molecular Formula | C12H12N2O4 |
| Purity | ≥95% |
| IUPAC Name | (2S)-2-(1,3-dioxopyrrolo[3,4-c]pyridin-2-yl)-3-methylbutanoic acid |
| InChI | InChI=1S/C12H12N2O4/c1-6(2)9(12(17)18)14-10(15)7-3-4-13-5-8(7)11(14)16/h3-6,9H,1-2H3,(H,17,18)/t9-/m0/s1 |
| InChIKey | KTDYLXVLROCGRL-VIFPVBQESA-N |
| SMILES | CC(C)[C@@H](C(=O)O)N1C(=O)C2=C(C1=O)C=NC=C2 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
