For research use only. Not for therapeutic Use.
(S)-TNG260(CAT: I040590) is a potent and selective small-molecule inhibitor targeting EP300/CBP histone acetyltransferase activity, designed to modulate transcriptional regulation via chromatin remodeling. This stereoisomer displays enhanced specificity and efficacy, making it a valuable tool for probing epigenetic mechanisms in cancer and developmental biology. Its inhibitory action on acetyltransferase function influences gene expression patterns, particularly in MYC-driven cancers. Supplied at high purity, (S)-TNG260 is suitable for in vitro research applications exploring transcriptional control, oncogenic pathways, and therapeutic epigenetic interventions. Ideal for academic and pharmaceutical research, it supports efforts to unravel chromatin dynamics and discover targeted epigenetic therapies.
| CAS Number | 2935964-93-3 |
| Synonyms | N-[2-amino-5-(4-fluorophenyl)phenyl]-4-(methylsulfonimidoyl)benzamide |
| Molecular Formula | C20H18FN3O2S |
| Purity | ≥95% |
| IUPAC Name | N-[2-amino-5-(4-fluorophenyl)phenyl]-4-(methylsulfonimidoyl)benzamide |
| InChI | InChI=1S/C20H18FN3O2S/c1-27(23,26)17-9-4-14(5-10-17)20(25)24-19-12-15(6-11-18(19)22)13-2-7-16(21)8-3-13/h2-12,23H,22H2,1H3,(H,24,25)/t27-/m0/s1 |
| InChIKey | JPFMYSJUFUEHBI-MHZLTWQESA-N |
| SMILES | CS(=N)(=O)C1=CC=C(C=C1)C(=O)NC2=C(C=CC(=C2)C3=CC=C(C=C3)F)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
