S-Propyl-2-thiobarbituric Acid

• CAT Number: R021011
• CAS Number: 145783-12-6
• Molecular Formula: C7H10N2O2S
• Molecular Weight: 186.23
• Purity: ≥95%
• Synonyms: 6-Hydroxy-2-(propylthio)-4(1H)-pyrimidinone; 2-(Propylthio)pyrimidine-4,6-diol
• Storage: -20°C
• IUPAC Name: 4-hydroxy-2-propylsulfanyl-1H-pyrimidin-6-one
• InChI: InChI=1S/C7H10N2O2S/c1-2-3-12-7-8-5(10)4-6(11)9-7/h4H,2-3H2,1H3,(H2,8,9,10,11)
• InChIKey: JNDANYQUROGPBP-UHFFFAOYSA-N
• SMILES: CCCSC1=NC(=CC(=O)N1)O

S-Propyl-2-thiobarbituric acid（Cat No.:R021011）is a sulfur-containing derivative of barbituric acid, characterized by the substitution of a propylthio group at the 5-position and a thiocarbonyl in place of one carbonyl group. This compound is recognized for its versatile role in medicinal chemistry, especially in the design of antioxidant and neuroprotective agents. Its unique structure contributes to high electron density and potential metal chelation activity. S-Propyl-2-thiobarbituric acid also serves as a building block in synthesizing heterocyclic compounds and evaluating oxidative stress-related pathways in pharmacological and biochemical research contexts.