(S)-Pregabalin Lactam

• CAT Number: R029944
• CAS Number: 181289-23-6
• Molecular Formula: C8H15NO
• Molecular Weight: 141.21
• Purity: ≥95%
• Synonyms: (S)-4-(2-Methylpropyl)-2-pyrrolidinone; (S)-4-(Isobutyl)pyrrolidin-2-one
• Storage: -20°C
• IUPAC Name: (4S)-4-(2-methylpropyl)pyrrolidin-2-one
• InChI: InChI=1S/C8H15NO/c1-6(2)3-7-4-8(10)9-5-7/h6-7H,3-5H2,1-2H3,(H,9,10)/t7-/m0/s1
• InChIKey: GUGXRXLTTHFKHC-ZETCQYMHSA-N
• SMILES: CC(C)CC1CC(=O)NC1

(S)-Pregabalin lactam (Cat No.: R029944) is a chiral, cyclic intermediate in the synthesis of (S)-pregabalin, a widely used anticonvulsant and neuropathic pain medication. The lactam structure results from cyclization of the γ-amino acid backbone, offering enhanced stability and ease of purification during synthesis. As a key building block, (S)-pregabalin lactam facilitates enantioselective production of the active pharmaceutical ingredient. Its well-defined stereochemistry ensures bioactivity and therapeutic efficacy, making it valuable in the development and manufacture of neurological and pain management drugs.