(S)-N-Despropyl Pramipexole

• CAT Number: R006173
• CAS Number: 106092-09-5
• Molecular Formula: C7H11N3S
• Molecular Weight: 169.25
• Purity: ≥95%
• Synonyms: (6S)-4,5,6,7-Tetrahydro-2,6-benzothiazolediamine; (S)-2,6-Diamino-4,5,6,7-?tetrahydrobenzothiazole; (S)-4,5,6,7-Tetrahydrobenzothiazole-2,6-diamine; Pramipexole Related Compound A USP
• Storage: -20°C
• IUPAC Name: (6S)-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
• InChI: InChI=1S/C7H11N3S/c8-4-1-2-5-6(3-4)11-7(9)10-5/h4H,1-3,8H2,(H2,9,10)/t4-/m0/s1
• InChIKey: DRRYZHHKWSHHFT-BYPYZUCNSA-N
• SMILES: C1CC2=C(CC1N)SC(=N2)N

(S)-N-Despropyl pramipexole (Cat No.: R006173) is a chiral metabolite and synthetic intermediate related to pramipexole, a dopamine agonist used in the treatment of Parkinson’s disease and restless legs syndrome. Lacking the N-propyl group present in pramipexole, this compound retains the essential aminothiazole structure and (S)-stereochemistry crucial for dopamine receptor interaction. It is primarily used in pharmacological studies to investigate dopamine receptor binding, structure-activity relationships, and metabolic pathways. Its role helps clarify the contribution of side-chain modifications to therapeutic efficacy and receptor selectivity.