For research use only. Not for therapeutic Use.
(S)-GSK852 (Cat No.: I040026) is a selective and potent inhibitor of receptor-interacting protein kinase 1 (RIPK1), a key regulator of necroptosis and inflammatory signaling. It is widely used in immunology and neurodegenerative disease research to study cell death pathways, including programmed necrosis. By inhibiting RIPK1, (S)-GSK852 helps explore therapeutic strategies for inflammatory diseases, autoimmune disorders, and neurodegeneration. Its high specificity makes it valuable for in vitro and in vivo studies, contributing to drug discovery efforts targeting necroptosis-related pathologies.
| CAS Number | 2305919-51-9 |
| Synonyms | (3S)-5-N-[(1R,5S)-3-hydroxy-6-bicyclo[3.1.0]hexanyl]-7-N,3-dimethyl-3-phenyl-2H-1-benzofuran-5,7-dicarboxamide |
| Molecular Formula | C24H26N2O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C24H26N2O4/c1-24(14-6-4-3-5-7-14)12-30-21-18(23(29)25-2)8-13(9-19(21)24)22(28)26-20-16-10-15(27)11-17(16)20/h3-9,15-17,20,27H,10-12H2,1-2H3,(H,25,29)(H,26,28)/t15?,16-,17+,20?,24-/m0/s1 |
| InChIKey | FNHHVPPSBFQMEL-KQHDFZBMSA-N |
| SMILES | CC1(COC2=C(C=C(C=C21)C(=O)NC3C4C3CC(C4)O)C(=O)NC)C5=CC=CC=C5 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
