(S)-CR8

• CAT Number: I012893
• CAS Number: 1084893-56-0
• Molecular Formula: C24H29N7O
• Molecular Weight: 431.53
• Purity: ≥95%
• Synonyms: (2S)-2-[[9-propan-2-yl-6-[(4-pyridin-2-ylphenyl)methylamino]purin-2-yl]amino]butan-1-ol
• InChI: InChI=1S/C24H29N7O/c1-4-19(14-32)28-24-29-22(21-23(30-24)31(15-27-21)16(2)3)26-13-17-8-10-18(11-9-17)20-7-5-6-12-25-20/h5-12,15-16,19,32H,4,13-14H2,1-3H3,(H2,26,28,29,30)/t19-/m0/s1
• InChIKey: HOCBJBNQIQQQGT-IBGZPJMESA-N
• SMILES: CC[C@@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=C(C=C3)C4=CC=CC=N4

(S)-CR8（Cat No.:I012893）is a selective inhibitor of the protein phosphatase 2A (PP2A) catalytic subunit, known for its role in regulating cellular signaling pathways. By inhibiting PP2A, (S)-CR8 modulates various processes, including cell proliferation, survival, and differentiation. It has been studied for its potential therapeutic applications in cancer and neurodegenerative diseases, where PP2A dysregulation is implicated in disease progression. (S)-CR8 is used to explore PP2A’s involvement in tumorigenesis and neuronal function, offering valuable insights into the development of targeted treatments for conditions such as Alzheimer’s disease and certain cancers.