(S)-(+)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE

• CAT Number: M021841
• CAS Number: 39637-99-5
• Molecular Formula: C10H8ClF3O2
• Molecular Weight: 252.62
• Purity: ≥95%
• Synonyms: (R)-(fi)-alpha-methoxy-alpha-trifluoromethylphenylacetylchloride;(+)-MTPA-CL;(+)-MOSHER/’S ACID CHLORIDE;MOSHER/’S ACID CHLORIDE;(+)-MOSHER/’S CHLORIDE;(S)-(+)-A-METHOXY-A-(TRIFLUOROMETHYL)PHENYLACETYL CHLORIDE;(S)-(+)-ALPHA-METHOXY-ALPHA-(TRIFLUOROM
• Storage: Store at -20°C
• IUPAC Name: (2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride
• InChI: InChI=1S/C10H8ClF3O2/c1-16-9(8(11)15,10(12,13)14)7-5-3-2-4-6-7/h2-6H,1H3/t9-/m0/s1
• InChIKey: PAORVUMOXXAMPL-VIFPVBQESA-N
• SMILES: COC(C1=CC=CC=C1)(C(=O)Cl)C(F)(F)F

(S)-(+)-Alpha-Methoxy-Alpha-Trifluoromethylphenylacetyl Chloride(CAT: M021841) is a versatile chiral derivatizing agent widely used in asymmetric synthesis and enantiomeric purity analysis. Featuring a trifluoromethylated phenylacetyl core with a reactive acyl chloride functionality, it enables stereoselective acylation of amines and alcohols, forming diastereomeric derivatives ideal for chiral resolution by NMR or chromatography. Its well-defined stereochemistry and strong electron-withdrawing groups contribute to high reactivity and resolution power. This reagent is essential in pharmaceutical development, fine chemical synthesis, and analytical method design, particularly for amino acid, peptide, and alcohol stereoisomer profiling.