S-Adenosyl-L-methionine tosylate

• CAT Number: R065242
• CAS Number: 52248-03-0
• Molecular Formula: C22H30N6O8S2
• Molecular Weight: 570.64
• Purity: ≥95%
• Synonyms: [(3S)-3-amino-3-carboxypropyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium;4-methylbenzenesulfonate
• IUPAC Name: [(3S)-3-amino-3-carboxypropyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium
• InChI: InChI=1S/C15H22N6O5S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/p+1/t7-,8+,10+,11+,14+,27?/m0/s1
• InChIKey: MEFKEPWMEQBLKI-AIRLBKTGSA-O
• SMILES: C[S+](CC[C@@H](C(=O)O)N)C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O

S-Adenosyl-L-methionine tosylate (Cat No.:R065242) is a stabilized salt form of S-adenosyl-L-methionine, a naturally occurring sulfonium compound involved in methyl group transfer, transsulfuration, and aminopropylation pathways. As a universal methyl donor, it plays a vital role in DNA, protein, and lipid methylation, influencing gene regulation and cellular metabolism. SAMe tosylate is widely studied for its therapeutic potential in liver disease, depression, and osteoarthritis. Its stabilized tosylate form enhances shelf-life and handling, making it a valuable biochemical tool for research in epigenetics, metabolism, and neuropsychiatric disorders.