(S)-3,5-Dihydroxylphenylglycine

• CAT Number: R040677
• CAS Number: 162870-29-3
• Molecular Formula: C8H9NO4
• Molecular Weight: 183.16
• Purity: ≥95%
• Synonyms: α-Amino-3,5-dihydroxybenzeneacetic Acid; (S)-DHPG; L-Di-meta-hydroxyphenylglycine
• Target: Neuronal Signaling
• Solubility: Soluble to 50 mM in sterile water
• Storage: Desiccate at -20C
• IUPAC Name: (2S)-2-amino-2-(3,5-dihydroxyphenyl)acetic acid
• InChI: InChI=1S/C8H9NO4/c9-7(8(12)13)4-1-5(10)3-6(11)2-4/h1-3,7,10-11H,9H2,(H,12,13)/t7-/m0/s1
• InChIKey: HOOWCUZPEFNHDT-ZETCQYMHSA-N
• SMILES: C1=C(C=C(C=C1O)O)C(C(=O)O)N

(S)-3,5-Dihydroxyphenylglycine (Cat No.: R040677) is a chiral amino acid derivative featuring two hydroxyl groups at the 3- and 5-positions of the phenyl ring and an (S)-configured glycine backbone. It is widely studied as a selective agonist or antagonist of metabotropic glutamate receptors (mGluRs), particularly in neuroscience research. Its structural mimicry of glutamate enables it to modulate synaptic signaling and neuroplasticity. This compound is valuable in pharmacological studies and receptor binding assays. Intended solely for laboratory research and biomedical investigation under controlled conditions.