(S)-3,3,3-Trifluoro-2-hydroxy-2-methylpropanoic acid

For research use only. Not for therapeutic Use.

  • CAT Number: L013642
  • CAS Number: 24435-45-8
  • Molecular Formula: C4H5F3O3
  • Molecular Weight: 158.08
  • Purity: ≥95%
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(S)-3,3,3-Trifluoro-2-hydroxy-2-methylpropanoic acid(Cat No.:L013642)is a chiral fluorinated hydroxy acid characterized by a trifluoromethyl group and a tertiary alcohol center. The (S)-configuration imparts optical activity, making it useful in asymmetric synthesis and as a chiral building block in pharmaceutical and agrochemical development. The trifluoromethyl group enhances metabolic stability and influences lipophilicity, while the hydroxyl and carboxylic acid groups provide reactive handles for derivatization, including esterification, amidation, or coupling reactions. Its unique structure makes it valuable in synthesizing fluorinated compounds with potential biological or physicochemical advantages.


CAS Number 24435-45-8
Molecular Formula C4H5F3O3
Purity ≥95%
IUPAC Name (2S)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoic acid
InChI InChI=1S/C4H5F3O3/c1-3(10,2(8)9)4(5,6)7/h10H,1H3,(H,8,9)/t3-/m0/s1
InChIKey CTGJACFEVDCYMC-VKHMYHEASA-N
SMILES C[C@](C(=O)O)(C(F)(F)F)O
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