For research use only. Not for therapeutic Use.
S 17092(Cat No.:I009252)is a selective and potent inhibitor of the protein tyrosine phosphatase (PTP) SHP-2, which plays a crucial role in regulating various signaling pathways involved in cell growth, differentiation, and survival. SHP-2 dysregulation has been implicated in various diseases, including cancer and developmental disorders. By inhibiting SHP-2, S 17092 can potentially block abnormal cell signaling, thus offering therapeutic potential in targeting cancers driven by SHP-2 mutations. The compound is being explored for its ability to modulate the immune response and treat diseases associated with aberrant SHP-2 activity.
CAS Number | 176797-26-5 |
Synonyms | [(2S,3aS,7aS)-2-(1,3-thiazolidine-3-carbonyl)-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-[(1R,2R)-2-phenylcyclopropyl]methanone |
Molecular Formula | C22H28N2O2S |
Purity | ≥95% |
IUPAC Name | [(2S,3aS,7aS)-2-(1,3-thiazolidine-3-carbonyl)-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-[(1R,2R)-2-phenylcyclopropyl]methanone |
InChI | InChI=1S/C22H28N2O2S/c25-21(18-13-17(18)15-6-2-1-3-7-15)24-19-9-5-4-8-16(19)12-20(24)22(26)23-10-11-27-14-23/h1-3,6-7,16-20H,4-5,8-14H2/t16-,17-,18+,19-,20-/m0/s1 |
InChIKey | NXSXRIHXEQSYEZ-KNJMJIDISA-N |
SMILES | C1CC[C@H]2[C@@H](C1)C[C@H](N2C(=O)[C@@H]3C[C@H]3C4=CC=CC=C4)C(=O)N5CCSC5 |
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