S 17092

For research use only. Not for therapeutic Use.

  • CAT Number: I009252
  • CAS Number: 176797-26-5
  • Molecular Formula: C22H28N2O2S
  • Molecular Weight: 384.53
  • Purity: ≥95%
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S 17092(Cat No.:I009252)is a selective and potent inhibitor of the protein tyrosine phosphatase (PTP) SHP-2, which plays a crucial role in regulating various signaling pathways involved in cell growth, differentiation, and survival. SHP-2 dysregulation has been implicated in various diseases, including cancer and developmental disorders. By inhibiting SHP-2, S 17092 can potentially block abnormal cell signaling, thus offering therapeutic potential in targeting cancers driven by SHP-2 mutations. The compound is being explored for its ability to modulate the immune response and treat diseases associated with aberrant SHP-2 activity.


CAS Number 176797-26-5
Synonyms

[(2S,3aS,7aS)-2-(1,3-thiazolidine-3-carbonyl)-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-[(1R,2R)-2-phenylcyclopropyl]methanone

Molecular Formula C22H28N2O2S
Purity ≥95%
IUPAC Name [(2S,3aS,7aS)-2-(1,3-thiazolidine-3-carbonyl)-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-[(1R,2R)-2-phenylcyclopropyl]methanone
InChI InChI=1S/C22H28N2O2S/c25-21(18-13-17(18)15-6-2-1-3-7-15)24-19-9-5-4-8-16(19)12-20(24)22(26)23-10-11-27-14-23/h1-3,6-7,16-20H,4-5,8-14H2/t16-,17-,18+,19-,20-/m0/s1
InChIKey NXSXRIHXEQSYEZ-KNJMJIDISA-N
SMILES C1CC[C@H]2[C@@H](C1)C[C@H](N2C(=O)[C@@H]3C[C@H]3C4=CC=CC=C4)C(=O)N5CCSC5
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