RYL-552S

For research use only. Not for therapeutic Use.

  • CAT Number: I043849
  • CAS Number: 1801444-69-8
  • Molecular Formula: C24H17F4NOS
  • Molecular Weight: 443.46
  • Purity: ≥95%
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RYL-552S(Cat No.:I043849)is a selective inhibitor of the Janus kinase 1 (JAK1) enzyme, which plays a pivotal role in immune cell signaling and inflammation. By inhibiting JAK1, RYL-552S effectively modulates immune responses and reduces the production of pro-inflammatory cytokines. This compound shows potential in the treatment of autoimmune diseases, such as rheumatoid arthritis and psoriasis, as well as inflammatory conditions. Its specificity for JAK1 allows for targeted therapeutic action, minimizing the impact on other JAK family members, thus offering a promising approach for managing chronic inflammatory diseases.


CAS Number 1801444-69-8
Synonyms

5-fluoro-3-methyl-2-[4-[[4-(trifluoromethylsulfanyl)phenyl]methyl]phenyl]-1H-quinolin-4-one

Molecular Formula C24H17F4NOS
Purity ≥95%
IUPAC Name 5-fluoro-3-methyl-2-[4-[[4-(trifluoromethylsulfanyl)phenyl]methyl]phenyl]-1H-quinolin-4-one
InChI InChI=1S/C24H17F4NOS/c1-14-22(29-20-4-2-3-19(25)21(20)23(14)30)17-9-5-15(6-10-17)13-16-7-11-18(12-8-16)31-24(26,27)28/h2-12H,13H2,1H3,(H,29,30)
InChIKey FGVWBGSMONDTRE-UHFFFAOYSA-N
SMILES CC1=C(NC2=C(C1=O)C(=CC=C2)F)C3=CC=C(C=C3)CC4=CC=C(C=C4)SC(F)(F)F
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