RUVBL1/2 ATPase-IN-1

• CAT Number: I043834
• CAS Number: 423128-55-6
• Molecular Formula: C28H28F3N5O
• Molecular Weight: 507.55
• Purity: ≥95%
• Synonyms: [5,7-dimethyl-6-[(4-methylphenyl)methyl]pyrazolo[1,5-a]pyrimidin-3-yl]-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
• InChI: InChI=1S/C28H28F3N5O/c1-18-7-9-21(10-8-18)15-24-19(2)33-26-25(17-32-36(26)20(24)3)27(37)35-13-11-34(12-14-35)23-6-4-5-22(16-23)28(29,30)31/h4-10,16-17H,11-15H2,1-3H3
• InChIKey: DWMRUZCWNNNCJM-UHFFFAOYSA-N
• SMILES: CC1=CC=C(C=C1)CC2=C(N3C(=C(C=N3)C(=O)N4CCN(CC4)C5=CC=CC(=C5)C(F)(F)F)N=C2C)C

RUVBL1/2 ATPase-IN-1（Cat No.:I043834）is a selective inhibitor of the RUVBL1 and RUVBL2 ATPases, which are involved in various cellular processes, including DNA repair, chromatin remodeling, and transcription regulation. These ATPases play critical roles in maintaining cellular homeostasis and are implicated in cancer progression, neurodegenerative diseases, and other disorders. By inhibiting RUVBL1/2, RUVBL1/2 ATPase-IN-1 disrupts these essential functions, potentially slowing down tumor growth and modulating cellular stress responses. This compound is being explored for its therapeutic potential in cancer research and treatment of diseases associated with RUVBL1/2 dysregulation.